Patients’ conditions can be complex. Managing DAPT should not be.
While there are many benefits of dual antiplatelet therapy (DAPT), there are also side effects and problems with patient compliance, which can lead to even more complications. 1 in 5 patients are at risk of bleeding, and this makes a simple one-treatment-fits-all very challenging.1
Striking the DAPT balance: How much is safe?
Long-term DAPT has been shown to increase bleeding and mortality risks, which is a greater concern for non-compliant patients or those at greater risk of bleeding.2
Furthermore, 1 out of every 3 patients have difficulty maintaining their DAPT regimen.3 Early discontinuation, as demonstrated in the EDUCATE registry, may result in blood clots and heart attacks. Finding the right DAPT balance is critical to reducing complications. An individualized approach is even more important than ever.
1. Genereux, et al. JACC 2015;66:1036-45.
2. Palmerini et al. JACC 2015; 65:1092-102.
3. Thim et al. BMC Cardiovasc Disord. 2014; 14:100.
Early discontinuation may result in heart attacks, blood clots and major bleeding
Cutlip DE, Dauerman H, et al. JACC: Cardiovascular Interventions. 2015; 8:404-10.